Northland House, at 3-5 Frederick Street in Belfast, is a six-story office building constructed in the 1960s. The site originally hosted the Belfast Lancasterian School, built in 1811 and demolished in 1963. Northland House has served various roles, including housing government offices and Northern Ireland Water until 2010. Designed in a mid-20th-century commercial style, its “T”-shaped structure includes multi-level extensions.

In January 2010, The Department of Finance & Personnel (DFPNI) submitted a planning application (Z/2010/0063/F) proposing the refurbishment and extension to the existing office building. This application was approved in February 2011.

In November 2024, a voluntary community consultation commenced for the planned Centre for Digital Healthcare Technology (CDHT) at Northland House. While the proposed development does not meet the criteria for a major planning application, a commitment has been made to ensure meaningful engagement throughout the consultation process.

The Centre for Digital Health Technology (CDHT) is one of five projects funded under the Belfast Region City Deal (BRCD) and aims to provide state-of-the-art research and development facilities, including laboratories, offices, and communal meeting spaces. The CDHT project will be developed by Ulster University (UU) in partnership with the Belfast Health and Social Care Trust (BHSCT).

In March 2025, a full planning application was submitted (LA04/2025/0477/F) proposing the erection of six storey building for Centre for Digital Health Technology (CDHT) research and development facility (Use Class B1), comprising laboratories, office spaces, communal meeting areas, public realm improvements to Frederick Street and associated works including demolition.