100 University Street is a extended 3 storey end terrace period property. The building is an end terrace edging onto Canterbury Street; however, the main frontage and pedestrian access is solely from University Street. 100 University Street is arranged over ground, first, second and third floors and provide a range of office suites.

In October 2014, Mr Lorne Campbell submitted a planning application (Z/2014/1304/F) proposing change of use from offices to 5 no self contained apartments, retaining the existing primary structure and building envelope. This application was approved in April 2015.

In January 2020, Mr Lorne Campbell submitted a planning application (LA04/2020/0213/F) proposing change of use from offices to 5 no. self contained apartments including new boundary wall for open space (renewal of Z/2014/1304/F).

In April 2024, Rowallane Properties Ltd submitted a planning application (LA04/2024/0619/F) proposing change of use from office space to 11 bedroom guest accommodation.